Measurement of serum transferrin by the γ−γ perturbed angular correlation method
Identifieur interne : 000478 ( Main/Exploration ); précédent : 000477; suivant : 000479Measurement of serum transferrin by the γ−γ perturbed angular correlation method
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Abstract
In this work, the average perturbed angular correlation integral attenuation factor G2 of the transferrin in the serums from the normals and the patients with liver cancer were determined using time integral perturbed angular correlation method (PAC). The average values of G2 were 0.1945±0.0155 for the cancer serum transferrin and 0.2865±0.0411 for the normal serum transferrin. The difference between these two groups is significant. Mathematical deduction and theoretical analysis suggested that the equivalent radius of the transferrin molecules in the serum of cancer patients becomes smaller than normal, because of a change in the molecular conformation. Similar results were also observed in experiments with rat serum transferrin.
DOI: 10.1007/BF02917411
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China</mods:affiliation><country xml:lang="fr" wicri:curation="lc">République populaire de Chine</country><wicri:regionArea>Shanghai Yang Pu District Tumor Hospital, Shanghai</wicri:regionArea><wicri:noRegion>Shanghai</wicri:noRegion></affiliation></author></titleStmt><publicationStmt><idno type="RBID">ISTEX:12011_1989_Article_BF02917411.pdf</idno><date when="1989">1989</date><idno type="doi">10.1007/BF02917411</idno><idno type="wicri:Area/Main/Corpus">000649</idno><idno type="wicri:Area/Main/Curation">000649</idno><idno type="wicri:Area/Main/Exploration">000478</idno></publicationStmt></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Equivalent radius of molecule</term><term>Indium-111</term><term>Iron</term><term>Liver cancer</term><term>Perturbed angular correlation</term><term>Serum</term><term>Transferrin</term></keywords><keywords scheme="Wicri" type="topic" xml:lang="fr"><term>Fer</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="eng">In this work, the average perturbed angular correlation integral attenuation factor G2 of the transferrin in the serums from the normals and the patients with liver cancer were determined using time integral perturbed angular correlation method (PAC). The average values of G2 were 0.1945±0.0155 for the cancer serum transferrin and 0.2865±0.0411 for the normal serum transferrin. The difference between these two groups is significant. Mathematical deduction and theoretical analysis suggested that the equivalent radius of the transferrin molecules in the serum of cancer patients becomes smaller than normal, because of a change in the molecular conformation. Similar results were also observed in experiments with rat serum transferrin.</div></front></TEI><mods xsi:schemaLocation="http://www.loc.gov/mods/v3 file:///applis/istex/home/loadistex/home/etc/xsd/mods.xsd" version="3.4" istexId="709195d45f600633cb716ca2831802fca84c2721"><titleInfo lang="eng"><title>Measurement of serum transferrin by the γ−γ perturbed angular correlation method</title><subTitle>Differences between normal and cancer serum</subTitle></titleInfo><name type="personal"><namePart type="given">Yongxian</namePart><namePart type="family">Wang</namePart><role><roleTerm type="text">author</roleTerm></role><affiliation>Shanghai Institute of Nuclear Research, Academia Sinica, PO Box 8204, Shanghai, China</affiliation></name><name type="personal"><namePart type="given">Xinbo</namePart><namePart type="family">Ni</namePart><role><roleTerm type="text">author</roleTerm></role><affiliation>Shanghai Institute of Nuclear Research, Academia Sinica, PO Box 8204, Shanghai, China</affiliation></name><name type="personal"><namePart type="given">Wenbiao</namePart><namePart type="family">Chen</namePart><role><roleTerm type="text">author</roleTerm></role><affiliation>Shanghai Institute of Nuclear Research, Academia Sinica, PO Box 8204, Shanghai, China</affiliation></name><name type="personal"><namePart type="given">Jinlong</namePart><namePart type="family">Xu</namePart><role><roleTerm type="text">author</roleTerm></role><affiliation>Shanghai Institute of Nuclear Research, Academia Sinica, PO Box 8204, Shanghai, China</affiliation></name><name type="personal"><namePart type="given">Chongwen</namePart><namePart type="family">Sun</namePart><role><roleTerm type="text">author</roleTerm></role><affiliation>Shanghai Institute of Nuclear Research, Academia Sinica, PO Box 8204, Shanghai, China</affiliation></name><name type="personal"><namePart type="given">Duanzhi</namePart><namePart type="family">Yin</namePart><role><roleTerm type="text">author</roleTerm></role><affiliation>Shanghai Institute of Nuclear Research, Academia Sinica, PO Box 8204, Shanghai, China</affiliation></name><name type="personal"><namePart type="given">Sheng</namePart><namePart type="family">Ding</namePart><role><roleTerm type="text">author</roleTerm></role><affiliation>Shanghai Yang Pu District Tumor Hospital, Shanghai, P.R. China</affiliation></name><typeOfResource>text</typeOfResource><genre>Original Paper</genre><originInfo><publisher>Humana Press, Totowa</publisher><dateCreated encoding="w3cdtf">1988-04-04</dateCreated><dateCaptured encoding="w3cdtf">1988-08-10</dateCaptured><dateValid encoding="w3cdtf">2008-06-07</dateValid><copyrightDate encoding="w3cdtf">1989</copyrightDate></originInfo><language><languageTerm type="code" authority="iso639-2b">eng</languageTerm></language><physicalDescription><internetMediaType>text/html</internetMediaType></physicalDescription><abstract lang="eng">In this work, the average perturbed angular correlation integral attenuation factor G2 of the transferrin in the serums from the normals and the patients with liver cancer were determined using time integral perturbed angular correlation method (PAC). The average values of G2 were 0.1945±0.0155 for the cancer serum transferrin and 0.2865±0.0411 for the normal serum transferrin. The difference between these two groups is significant. Mathematical deduction and theoretical analysis suggested that the equivalent radius of the transferrin molecules in the serum of cancer patients becomes smaller than normal, because of a change in the molecular conformation. Similar results were also observed in experiments with rat serum transferrin.</abstract><subject lang="eng"><genre>Index Entries</genre><topic>Liver cancer</topic><topic>serum</topic><topic>iron</topic><topic>Indium-111</topic><topic>transferrin</topic><topic>perturbed angular correlation</topic><topic>equivalent radius of molecule</topic></subject><relatedItem type="series"><titleInfo type="abbreviated"><title>Biol Trace Elem Res</title></titleInfo><titleInfo><title>Biological Trace Element Research</title><partNumber>Year: 1989</partNumber><partNumber>Volume: 22</partNumber><partNumber>Number: 1</partNumber></titleInfo><genre>Archive Journal</genre><originInfo><dateIssued encoding="w3cdtf">1989-10-01</dateIssued><copyrightDate encoding="w3cdtf">1989</copyrightDate></originInfo><subject usage="primary"><topic>Life Sciences</topic><topic>Biochemistry, general</topic><topic>Biotechnology</topic><topic>Nutrition</topic><topic>Oncology</topic></subject><identifier type="issn">0163-4984</identifier><identifier type="issn">Electronic: 1559-0720</identifier><identifier type="matrixNumber">12011</identifier><identifier type="local">IssueArticleCount: 11</identifier><recordInfo><recordOrigin>The Humana Press Inc., 1989</recordOrigin></recordInfo></relatedItem><identifier type="doi">10.1007/BF02917411</identifier><identifier type="matrixNumber">Art1</identifier><identifier type="local">BF02917411</identifier><accessCondition type="use and reproduction">MetadataGrant: OpenAccess</accessCondition><accessCondition type="use and reproduction">AbstractGrant: OpenAccess</accessCondition><accessCondition type="restriction on access">BodyPDFGrant: Restricted</accessCondition><accessCondition type="restriction on access">BodyHTMLGrant: Restricted</accessCondition><accessCondition type="restriction on access">BibliographyGrant: Restricted</accessCondition><accessCondition type="restriction on access">ESMGrant: Restricted</accessCondition><part><extent unit="pages"><start>1</start><end>7</end></extent></part><recordInfo><recordOrigin>The Humana Press Inc., 1989</recordOrigin><recordIdentifier>12011_1989_Article_BF02917411.pdf</recordIdentifier></recordInfo></mods></record>Pour manipuler ce document sous Unix (Dilib)
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